Team
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Fundus photograph-based deep learning algorithms in detecting diabetic retinopathy
Raman R, Srinivasan S, Virmani S, Sivaprasad S, Rao C, Rajalakshmi R.
Eye (Lond).2019 Jan;33(1):97-109.
Diagnostic Accuracy of Community-Based Diabetic Retinopathy Screening with an Offline Artificial Intelligence System on a Smartphone
Sundaram Natarajan, Astha Jain, Radhika Krishnan, Ashwini Rogye, Sobha Sivaprasad.
JAMA Ophthalmol.2019;137(10):1182‐1188.
A review of studies utilising retinal photography on the global prevalence of Diabetes-related retinopathy between 2015 and 2018
Thomas RL, Halim S, Gurudas S, Sivaprasad S, Owens DR.
Diabetes Res Clin Pract. 2019 Nov;157:107840.
Achieving a Stable High Surface Excess of Glucose Oxidase on Pristine Multiwalled Carbon Nanotubes for Glucose Quantification
Bose Dinesh, K. S. Shalini Devi, Uma Maheswari Krishnan.
ACS Applied Biomaterials, 2019, 2 (4), 1740-1750.
Metabolic Syndrome—An Emerging Constellation of Risk Factors: Electrochemical Detection Strategies.
M.Sasya, K.S.Shalini Devi, Jayanth Babu K, J.B.B. Rayappan, U.M.Krishnan.
MDPI Sensors, 2019 Dec 23;20(1). pii:E103
Capacity building for universal eye health coverage in South East Asia beyond 2020.
Das T, Keeffe J, Sivaprasad S, Rao GN.
Eye (Lond). 2020 Feb
Tackling diabetic retinopathy from the grassroots.
Sivaprasad S.
Indian J Ophthalmol. 2020 Feb;68(Suppl 1):S8-S9.
Evaluating the performance of the Indian Diabetes Risk Score in different ethnic groups.
Nugawela MD, Sivaprasad S, Viswanathan M, Rajalakshmi R, Netuveli G
Diabetes Technology and Therapeutics, Mar 2020 Vol 22 No 4. IF:4.488
Chemical sensors based on metal oxides
K.S. Shalini Devi, Aadhav Anantharamakrishnan, U.M. Krishnan, J. Yakhmi
Smart Sensors for Environmental and Medical Applications, Ed: Hamida Hallil Abbas & Hadi Heidari, April 2020 Wiley-IEEE Press, ISBN: 978-1-119-58734-7.
Emerging Vistas on Electrochemical Detection of Diabetic Retinopathy Biomarkers.
K. S. Shalini Devi, M. Sasya, U.M. Krishnan
TrAC Trends in Analytical Chemistry, Apr 2020 v.125 pp. 115838.IF:8.428
The ORNATE India Project: United Kingdom-India Research Collaboration to tackle visual impairment due to diabetic retinopathy.
Sivaprasad S, Ram an R, Conroy D, Mohan V, Wittenberg R, Rajalakshmi R, Majeed A, Krishnakumar S, Prevost T, Parameswaran S, Turowski P, Maheswari U, Khobragade R, Netuveli G, Sadanandan R, Greenwood J, Ramasamy K, Rao M, Bergeles C, Das T for the ORNATE India Project Group.
Eye (Lond).12 May 2020, 34(7):1279-1286
Correlation between markers of renal function and sight threatening diabetic retinopathy in type 2 diabetes: a longitudinal study in an Indian clinic population.
Ramachandran Rajalakshmi. Coimbatore Subramanian Shanthi Rani, Ulagamathesan Venkatesan, Ranjit Unnikrishnan, Ranjit Mohan Anjana, Saravanan Jeba Rani, Ganesan Uma Sankari, Sobha Sivaprasad, Rajiv Raman, Viswanathan Mohan.
BMJ Open Diab Res Care 2020;8:e001325.
Multi-centre risk-based screening for diabetes and its complications
Complex interventions to implement a diabetic retinopathy care pathway in the public health system in Kerala: a hybrid effectiveness-implementation study (Nayanaadram project)
Circulating biomarkers to detect sight-threatening diabetic retinopathy
Prevalence and incidence of visual impairment in patients with proliferative diabetic retinopathy in India
Rehana Khan, Shruti Chandra, Ramachandran Rajalakshmi, Padmaja Kumari Rani, Giridhar Anantharaman, Alok Sen, Abhishek Desai, Rupak Roy, Sundaram Natarajan, Lanin Chen, Gajendra Chawla, Umesh Chandra Behera, Lingam Gopal, Sarega Gurudas, Sobha Sivaprasad and Rajiv Raman
Scientific Reports 10,10513 (2020)
Deep Learning-Based Segmentation and Quantification of Retinal Capillary Non-Perfusion on Ultra-Wide-Field Retinal Fluorescein Angiography
Joan M. Nunez do Rio, Piyali Sen, Rajna Rasheed, Akanksha Bagchi, Luke Nicholson Adam M. Dubis, Christos Bergeles and Sobha Sivaprasad.
J. Clin. Med. 2020, 9(8), 2537
Early SD-OCT biomarkers to confirm fellow eye changes in asymmetric Type 2 Macular Telangiectasia: a case control study (India MacTel Report 1)
Alex D, Giridhar A, Gopalakrishnan M, Manayath G, Amar S, Raman R, Sreenivasan R, Ayachit A, Sivaprasad S.
Retina. 2020 Aug 12
Evaluation of real‑world early response of DMO to aflibercept therapy to inform future clinical trial design of novel investigational agents
Sandra Halim, Sarega Gurudas, Shruti Chandra, John Greenwood, Sobha Sivaprasad
Scientific Reports 10, 16499 (2020)
Microfluidic immunosensor for detection of Cystatin C for diagnosis of diabetic retinopathy in human serum
K. S. Shalini Devi, Uma Maheswari Krishnan
Microchim Acta 187, 585 (2020)
Diabetic Retinopathy Environment-Wide Association Study (EWAS) in NHANES 2005–2008
Kevin Blighe, Sarega Gurudas, Ying Lee and Sobha Sivaprasad
J. Clin. Med. 2020, 9, 3643
A multi-centre statistical and economic modelling of risk-based stratified and personalised screening for diabetes and its complications in India (SMART India).
Sobha Sivaprasad, Rajiv Raman, Ramachandran Rajalakshmi, Viswanathan Mohan, Deepa Mohan, Taraprasad Das, Kim Ramasamy, Toby Prevost, Raphael Wittenberg, Gopal Netuveli, Gopal Lingam, Wasim Hanif, Radha Ramakrishnan, Jayashree Ramu, Janani Surya and Dolores Conroy for the SMART India Study Collaborators.
BMJ Open. 2020; 10(12):e039657
Need for vitreous surgeries in proliferative diabetic retinopathy in 10 years follow-up: India Retinal Disease Study (IRDS) group Report no.2
Khan R. Surya J. Rajalakshmi R. Rani P.K. Anantharaman G. Gopalakrishnan M. Sen A. Desai A, Roy R. Natarajan S. Chen L. Chawla G. Behera U.C. Gopal L. Muralidharan V. Sivaprasad S and Raman R.
Ophthalmic Research 2020 Nov 3
Impact on health and provision of healthcare services during the COVID-19 lockdown in India: a multicentre cross-sectional study
Rajiv Raman, Ramachandran Rajalakshmi, Janani Surya, Radha Ramakrishnan, Sobha Sivaprasad, Dolores Conroy, Jitendra Pal Thethi,V Mohan and Gopalakrishnan Netuveli
BMJ Open 2021;11:e043590.
Impact of treatment of diabetic macular edema on visual impairment in people with diabetes mellitus in India
Sucheta Kulkarni, Rajalakshmi Ramachandran, Sobha Sivaprasad, Padmaja Kumari Rani, Umesh C Behera, Vignesh T P, Gajendra Chawla, Manisha Agarwal, Sheena Liz Man, Kim Ramasamy and Rajiv Raman
Ind J Ophthalmol 2021;69:671-6
Associations between attainment of incentivised primary care indicators and incident sight-threatening diabetic retinopathy in the United Kingdom: A population-based historical cohort study
Ailsa J McKay, Laura H Gunn, Manjula Nugawela, Thirunavukkarasu Sathish, Azeem Majeed, Eszter Vamos, German Molina, Sobha Sivaprasad
Diabetes Obesity and Metabolism 2021 Feb 10.
Associations between attainment of incentivised primary care indicators and incident diabetic retinopathy in the United Kingdom: A population-based historical cohort study
Ailsa J McKay, Laura H Gunn, Manjula Nugawela, Thirunavukkarasu Sathish, Azeem Majeed, Eszter Vamos, German Molina, Sobha Sivaprasad
BMC Med, 2021:19; 93
Deep Learning for Gradability Classification of Handheld, Non-mydriatic Retinal Images
Paul Nderitu, Joan M. Nunez do Rio, Rajna Rasheed, Rajiv Raman, Ramachandran Rajalakshmi, Christos Bergeles, Sobha Sivaprasad for the SMART India study group.
Scientific Reports 11, 9469 (2021)
Outcomes of neovascular glaucoma in eyes presenting with moderate to good visual potential
Padmaja Kumari Rani, Piyali Sen, Niroj Kumar Sahoo, Sirisha Senthil, Renuka Chakurkar, Manju Anup,Umesh Chandra Behera Sobha Sivaprasad and Taraprasad Das
Int Ophthalmol (2021)
Diabetic retinopathy screening guidelines in India- All India Ophthalmological Society diabetic retinopathy task force and Vitreoretinal Society of India Consensus Statement
Rajiv Raman, Kim Ramasamy, Ramachandran Rajalakshmi; Sobha Sivaprasad, and S Natarajan.
Ind J Ophthal. March 2021 – Volume 69 – Issue 3 – p 678-688
Existing point-of-care diagnostics: merits and demerits
S. Nellaiappan, U. M. Krishnan.
Book Chapter in Disposable Electrochemical Sensors for Healthcare Monitoring: Material Properties and Design, Royal Society of Chemistry, May 5th, 2021
Recently updated global diabetic retinopathy screening guidelines: commonalities, differences, and future possibilities
Das T, Takkar B, Sivaprasad S, Thanksphon T, Taylor H, Wiedemann P, Nemeth J, Patanjali Nayar P, Kumari Rani P, Khandekar R
Eye (Lond) published online 11 May
Indicators of visual prognosis in diabetic macular oedema
Sagnik Sen, Kim Ramasamy and Sobha Sivaprasad
J. Pers. Med. 2021, 11(6), 449
Complex interventions to implement a diabetic retinopathy care pathway in the public health system in Kerala: an effectiveness-implementation protocol of the Nayanamritham project.
Sobha Sivaprasad, Gopal Netuveli, Raphael Wittenberg, Rajan Khobragade, Rajeev Sadanandan, Bipin Gopal, Lakshmi Premnazir, Dolores Conroy, Jyotsna Srinath, Radha Ramakrishnan, Simon George, Vasudeva Iyer Sahasranamam for the Nayanamritham Project Collaborators.
BMJ Open 2021; 1(6):e040577
Diagnostic Circulating Biomarkers to Detect Vision-Threatening Diabetic Retinopathy: Potential Screening Tool of the Future? A review
Karen Frudd, Sobha Sivaprasad, Rajiv Raman, Subramanian Krishnakumar, Yeddula Rebecca Revathy, Patric Turowski
Acta Ophthalmologica 2021, Jul 16.
Development and validation of resource-driven risk prediction models for incident chronic kidney disease in type 2 diabetes
Sarega Gurudas, Manjula Nugawela, A Toby Prevost, Thirunavukkarasu Sathish, Rohini Mathur, J M Rafferty, Kevin Blighe, Ramachandran Rajalakshmi, Dr. Anjana R Mohan, Jebarani Saravanan, Azeem Majeed, Viswanthan Mohan, David R Owens, John Robson, and Sobha Sivaprasad.
Scientific Reports 2021;11:13654
Is immediate treatment necessary for diabetic macular edema after pars plana vitrectomy for tractional complications of proliferative diabetic retinopathy?
Umesh Chandra Behera, Taraprasad Da, Sobha Sivaprasad, Padmaja Kumari Rani, Rajiv Raman, Manisha Agarwal, Tushar Agarwal, Suman Sahu, Harshit Vaidya and Bhavik Panchal.
International Ophthalmology 2021 Jun 25
Microvascular changes precede visible neurodegeneration in fellow eyes of patients with asymmetric type 2 macular telangiectasia.
Kiran Chandran, Anantharaman Giridhar, Mahesh Gopalakrishnan and Sobha Sivaprasad
Eye (Lond). 2021 Jul 29
Ethnic disparities in the development of sight-threatening diabetic retinopathy in a UK multi-ethnic population with diabetes: an observational cohort study
Manjula D Nugawela, Sarega Gurudas, A Toby Prevost, Rohini Mathur, John Robson, Wasim Hanif, Azeem Majeed, Sobha Sivaprasad
J. Pers. Med. 2021, 11(8), 740
Identifying Peripheral Neuropathy in Colour Fundus Photographs Based on Deep Learning
Diego R. Cervera, Luke Smith, Luis Diaz-Santana, Meenakshi Kumar, Rajiv Raman,and Sobha Sivaprasad
Diagnostics 2021,11,1943
Bridging the valley of death between research and implementing a systematic diabetic retinopathy screening program in low- and medium-income countries-a perspective
Sobha Sivaprasad, Dolores Conroy and Taraprasad Das
Indian J. Ophthalmol. 2021; 69(11):3068-3071
Diabetic macular edema treatment guidelines in India: All India Ophthalmological Society diabetic retinopathy task force, Vitreoretinal Society of India Consensus Statement
Giridhar, Sneha; Verma, Lalit; Rajendran, Anand; Bhende, Muna; Goyal, Mallika; Ramasamy, Kim; Rajalakshmi, R, Padmaja; Natarajan, Sundaram; Palanivelu, Mahesh Shanmugam; Raman, Rajiv and Sivaprasad, Sobha
Indian J. Ophthamol. 2021;69(11):3076-3086
Various models for diabetic retinopathy screening that can be applied to India
Rajalakshmi, Ramachandran, Prathiba, Vijayaraghavan, Rani, Padmaja Kumar, Mohan, Viswanathan
Indian J. Ophthalmol. 2021;69(11): 2951-2958
Barriers in establishing systematic diabetic retinopathy screening through telemedicine in low- and middle-income countries
Yim, Daniel, Chandra, Shruti; Sondh, Rajan; Thottarath, Sridevi; Sivaprasad, Sobha
Indian J. Ophthalmol. 2021;69(11): 2987-2992
ORNATE India: Building research capacity and capability to tackle the burden of diabetic retinopathy-related blindness in India
Dolores Conroy, Radha Ramakrishnan, Rajiv Raman, Rajalakshmi Ramchandran, Padmaja Rani, Kim Ramasamy, Viswanathan Mohan, Taraprasad Das, Rajeev Sadanandan and Sobha Sivaprasad.
Indian J. Ophthalmol. 2021;69(11):3058-3063
Adding screening for “end organ damage” to the noncommunicable disease package in primary care
Rajeev Sadanandan and Sobha Sobhavaprasad,
Indian J. Ophthalmol. 2021;69(11):3064-3067
Identification of risk factors for targeted diabetic retinopathy screening to urgently decrease the rate of blindness in people with diabetes in India
Sagnik Sen, Kim Ramasamy, TP Vignesh, Naresh B Kannan, Sobha Sivaprasad, Ramachandran Rajalakshmi , Rajiv Raman , Viswanathan Mohan, Taraprasad Das, Iswarya Man.
Indian J.Ophthalmol.2021; 69(11):3156-3164
Severity of diabetic retinopathy and its relationship with age at onset of diabetes mellitus in India: A multicentric study
Deepika C Parameswarappa, Ramachandran Rajalakshmi, Ashik Mohamed, Sanagavarapu Kavya, Haripriya Munirathnam, George Manayath, Mathangi Ashok Kumar, Rajiv Raman, T P Vignesh, Kim Ramasamy, Sheena Mani, Alankrita Muralidhar, Manisha Agarwal, Giridhar Anantharaman, Neha Bijlani, Gajendra Chawla, Alok Sen, Sucheta Kulkarni, Umesh C Behera, Sobha Sivaprasa, Taraprasad Das, Padmaja Kumari Rani
Indian J. Ophthalmol. 2021;69(11):3255-3261
Prevalence and risk factors of diabetic retinopathy in a district-wide teleophthalmology care model integrated within primary care in Kerala: Nayanamritham project
Sobha Sivaprasad, Vasudeva Iyer Sahasranamam, M.S; Simon George; Rajeev Sadanandan; Bipin Gopal; Lakshmi Premnazir; Dolores Conroy; Jyotsna Srinath; Radha Ramakrishnan; Raphael Wittenberg; Gopal Netuveli
J. Clin. Med. 2021 10(24): 5903
Diabetic macular ischaemia- a new therapeutic target?
Chui Ming Gemmy Cheung, Amani Fawzi, Kelvin YC. Teo, Hisashi Fukuyama, Sagnik Sen, Wei-Shan Tsai, Sobha Sivaprasad
Progress in Retinal and Eye Research 2021 Dec 11;101033.
Evaluation of a deep learning algorithm for grading diabetic retinopathy on non-mydriatic retinal images acquired by field workers in community screening in India
Joan M Nunez do Rio, Paul Nderitu, Christos Bergeles, Sobha Sivaprasad, Gavin SW Tan, Rajiv Raman, for the SMART India Study Collaborators
J. Clin. Med. 2022, 11(3), 614
Prevalence and risk factors for diabetic retinopathy in prediabetes in Asian Indians
Ramachandran Rajalakshmi, Ganesan Uma Sankari, Sobha Sivaprasad, Ulagamathesan Venkatesan, Satyavani Kumpatla, Coimbatore Subramanian Shanthirani, Vijay Viswanathan and Viswanathan Mohan
J Diabetes Complications. 2022 Jan 23;108131
SAARC Academy of Ophthalmology-Tailoring Clinical Standards for Diabetic Retinopathy Care to Available Resources
Eli Pradhan, Dipak Nag,Deepanee Wewalwals,Subash Pokharel, Dolores Conroy, Divya Pradhana, Sobha Sivaprasad, Rajarvardhan Azad, Hussain Ahmad Khaquan,Bhim Rai, Haji Hussain Frogh, Fathimath Shaamaly Jaufar, Anadi Khatril and Rajiv Raman.
Nepal J. Ophthal 2022; Vol 14(27):130-09
Tele-Ophthalmology Versus Face-to-Face Retinal Consultation for Assessment of Diabetic Retinopathy in Diabetes Care Centers in India: A Multicenter Cross-Sectional Study
Ramachandran Rajalakshmi, Ganesan UmaSankari, Vijayaraghavan Prathiba, Ranjit Mohan Anjana, Ranjit Unnikrishnan, Ulagamathesan Venkatesan, Saravanan Jeba Rani, Coimbatore Subramanian Shanthirani, Sobha Sivaprasad and Viswanathan Mohan.
Diabetes Technol Ther. 2022 Apr 13.
Multicenter Evaluation of Diagnostic Circulating Biomarkers to Detect Sight-Threatening Diabetic Retinopathy
Sarega Gurudas, Karen Frudd, Jayapal Jeya Maheshwari, Yeddula Rebecca Revathy, Sobha Sivaprasad, Shruthi Mahalakshmi Ramanathan, Vignesh Pooleeswaran, A. Toby Prevost, Eleni Karatsai, Sandra Halim, Shruti Chandra, Paul Nderitu, Dolores Conroy, Subramanian Krishnakumar, Sowmya Parameswaran,
Kuppamuthu Dharmalingam, Kim Ramasamy, Rajiv Raman, Colin Jones, Haralabos Eleftheriadis, John Greenwood and Patric Turowski.
JAMA Ophthalmol. 2022 Jun 1;140(6):587-597
Development and validation of predictive risk models for sight threatening diabetic retinopathy in patients with type 2 diabetes to be applied as triage tools in resource limited settings
Manjula D. Nugawela, Sarega Gurudas, A. Toby Prevost, Rohini Mathur, John Robsone, Thirunavukkarasu Sathish, J.M. Rafferty, Ramachandran Rajalakshmi, Ranjit Mohan Anjana, Saravanan Jebarani, Viswanathan Mohan, David R. Owens and Sobha Sivaprasa
eClinicalMedicine Volume 51, September 2022, 101578
Prevalence of diabetic retinopathy in India stratified by known and undiagnosed diabetes, urban–rural locations, and socioeconomic indices: results from the SMART India population-based cross-sectional screening study
Rajiv Raman, Joana C Vasconcelos, Ramachandran Rajalakshmi, A Toby Prevost,
Kim Ramasamy, Viswanathan Mohan, Deepa Mohan, Padmaja K Rani, Dolores Conroy, Taraprasad Das, Sobha Sivaprasad, on behalf of the SMART India Study Collaborators
Lancet Global Health, 2022 Dec;10(12):e1764-e1773
Using deep learning to detect diabetic retinopathy on handheld non-mydriatic retinal images acquired by field workers in community settings
Joan M. Nunez do Rio, Paul Nderitu, Rajiv Raman, Ramachandran Rajalakshmi, Ramasamy Kim, Padmaja K. Rani, Sobha Sivaprasad & Christos Bergeles for the SMART India Study Group
Scientif Reports13, 1392 (2023)
OUTER FOVEAL DEFECTS IN TYPE-2 MACULAR TELANGIECTASIA
Kiran Chandran, Anantharaman Giridhar, M S Gayathri, Meghana Antison, Mahesh Gopalakrishnan and Sobha Sivaprasad.
Retina 2023 Jan 1;43(1):111-119
Estimating the costs of blindness and moderate to severe visual impairment among people with diabetes in India
S. Redding, R. Anderson, R. Raman, S. Sivaprasad and R. Wittenberg
BMJ Open 2023 Vol. 13 Issue 6 Pages e063390
Role of cystatin C in the detection of sight-threatening diabetic retinopathy in Asian Indians with type 2 diabetes
Thyparambil Aravindakshan, Pramod Kumar, Sobha Sivaprasad, Ulagamathesan Venkatesan, Viswanathan Mohan, Ranjit Mohan Anjana, Ranjit Unnikrishnan, Juhy Cherian, Anantharaman Giridhar, Mahesh Gopalakrishnan, and Ramachandran Rajalakshmi.
Journal of Diabetes and its Complications, Volume 37, Issue 8,2023
Relation of interdigitation zone changes and right-angle vessels in Macular Telangiectasia Type-2 (MacTel)
Kiran Chandran, Anantharaman Giridhar, Mahesh Gopalakrishnan & Sobha Sivaprasad
Eye (2023) volume 37, pages 2977–2986
National prevalence of vision impairment and blindness and associated risk factors in adults aged 40 years and older with known or undiagnosed diabetes: results from the SMART-India cross-sectional study,
Sarega Gurudas, Joana C Vasconcelos, A Toby Prevost, Rajiv Raman,Ramachandran Rajalakshmi, Kim Ramasamy, Viswanathan Mohan, Padmaja K Rani,Taraprasad Das, Dolores Conroy, Robyn J Tapp, Sobha Sivaprasad, on behalf of SMART-India Study Collaborators.
The Lancet Global Health, Volume 12, Issue 5, 2024, Pages e838-e847,